站内查询
您现在的位置是:主页 > 威尼斯官方app手游 > 日常饮食能快速改变人类精子质量
日常饮食能快速改变人类精子质量
2020-01-08 00:30  www.equintos.com

  世界范围的调查发现健康男性的精子质量逐年下降。精子质量可能受到一些环境和生活方式因素的损害,其中肥胖和相关疾病,如2型糖尿病,是精子质量差的众所周知的危险因素。在先前的研究中,科学家们发现,雄性果蝇在交配前不久摄入了过量的糖分,它们往往产生超重的后代。

A worldwide survey found that sperm quality in healthy men declined year by year. sperm quality may be impaired by some environmental and lifestyle factors, among which obesity and related diseases such as type 2 diabetes are well-known risk factors for poor sperm quality. In previous studies, scientists found that male fruit flies ingested excess sugar shortly before mating, and they tended to produce overweight offspring.

  对小鼠的研究表明,被称为tsRNA(tRNAderivedsmallRNA)的RNA小片段对下一代的表观遗传调控起着一定的作用。这些RNA片段存在于许多物种的精子中,包括人类、果蝇和小鼠的精子非常丰富。迄今为止,其功能尚未清楚。一般来说,RNA在建立表观遗传状态方面起着至关重要的作用,包括异染色质形成和生殖细胞中的转座沉默。人类精子的tsRNA是否对饮食干预有反应,是否与精子质量的变化有关,尚未对此进行调查。

studies on mice have shown that small rna fragments known as tsrna (trna derive dsmall rna) play a role in epigenetic regulation of the next generation. These RNA fragments are found in the sperm of many species, including humans, fruit flies, and mice with very abundant sperm. so far, its function is not clear. in general, rna plays a crucial role in establishing epigenetic states, including heterochromatin formation and transposable silencing in germ cells. whether tsrna of human sperm responds to dietary interventions and is associated with changes in sperm quality has not been investigated.

  瑞典Link?pingUniversity的研究小组旨在调查高糖摄入量是否会影响人类精子中的RNA片段。他们的成果于近日发表在PLOSBiology上,题为:Humanspermdisplaysrapidresponsestodiet。

Swedish Link? The team from ping university looked at whether high glucose intake affects rna fragments in human sperm. Their results were recently published in PLOS Biology entitled Humanspermdisplaysrapidresponsestodiet.

  这项研究调查了15名正常、不吸烟的年轻人,他们遵循一种饮食,在两周内从科学家那里得到所有食物。饮食是基于北欧健康饮食的营养建议,但有一个例外:在第二周,研究人员每天添加约升碳酸饮料或450克糖果的糖。在研究开始时、第一周(他们吃健康饮食期间)和第二周(参与者额外摄入大量糖时)对精子质量和其他健康指标进行了调查。在研究开始时,三分之一的参与者精子活动能力低下。活力是影响精子质量的几个因素之一,而低精子运动性人群在研究中与一般人群的这一比例相当。研究人员惊奇地发现,在研究过程中,所有参与者的精子活动都变得正常。

The study looked at 15 normal, non-smoking young people who followed a diet and got all the food from scientists within two weeks. Diets are based on nutritional advice from a healthy Nordic diet, with one exception: in the second week, researchers add about a litre of carbonated drink or 450g of sugar to their day. sperm quality and other health indicators were investigated at the beginning of the study, during the first week (during which they ate a healthy diet), and in the second week (when participants took an extra large amount of sugar). At the beginning of the study, a third of the participants had low sperm motility. motility is one of several factors affecting sperm quality, and the low sperm motility population in the study corresponded to this proportion in the general population. The researchers were surprised to find that sperm activity became normal in all participants during the study.

  研究人员还发现,与精子活力相关的小RNA片段也发生了变化。他们现在计划继续这项工作,并调查男性生育力和精子中的RNA片段之间是否有联系。他们还将确定RNA代码是否可用于新的诊断方法,以测量精子在体外受精期间的质量。

The researchers also found that small RNA fragments associated with sperm motility also changed. They now plan to continue the work and investigate whether there is a link between male fertility and RNA fragments in sperm. They will also determine whether the RNA code can be used in new diagnostic methods to measure the quality of sperm during IVF.

  综合来说,研究表明,精子活力可以在短时间(两周)内改变,并且似乎与饮食密切相关。这具有重要的临床意义。下一步科学家继续研究以期可以将变化与精子中的特定分子联系起来。

Taken together, studies have shown that sperm motility can change in a short time (two weeks) and appears to be closely related to diet. which has important clinical significance. The next step is for scientists to continue research to link changes to specific molecules in sperm.